Ptpn4 - SNV Details



 Gene Information 
Gene Name Ptpn4
Gene Description protein tyrosine phosphatase, non-receptor type 4 [Source:MGI Symbol;Acc:MGI:1099792]
MGI phenotype Mice homozygous for a null allele exhibit impaired coordination, abnormal eye blink conditioning behavior, and reduced long term depression.
Uniprot Name
CCDS Name
Gene GO
protein dephosphorylation; cytoplasm; dephosphorylation; protein tyrosine phosphatase activity; extrinsic to membrane; protein binding; cytoskeleton; internal side of plasma membrane; non-membrane spanning protein tyrosine phosphatase activity; cytoskeletal protein binding; phosphatase activity
Homolog in other species PTPN4
Immgen Expression
MEDIAN(LOWER IN MYELOID GROUP, DC.LC.SK)
Gnf Expression
MEDIAN(HIGH IN TESTIS)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000026384
Chromosome 1
Coordinate 119,675,547     (Assembly: GRCm38)    
Ref Base A
Var Base C
Zygosity Heterozygous
Read Depth 23
Allele Frequency
A:R0.48
C:V0.52
Amino Acid Change Disrupted splicing
Splice Position 2
Sample ID IGL01870
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 33 Other Mutations

 Predictions 
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved