Mki67 - SNV Details



 Gene Information 
Gene Name Mki67
Old Gene Names for Mki67 D630048a14rik
Gene Description antigen identified by monoclonal antibody Ki 67 [Source:MGI Symbol;Acc:MGI:106035]
Uniprot Name
CCDS Name
Gene GO
DNA metabolic process; chromosome
centromeric region; nuclear part; cytoplasm; cell proliferation; meiosis; condensed chromosome; protein C-terminus binding; intracellular; cellular response to heat; protein binding; nucleus; nucleolus; organ regeneration
Homolog in other species MKI67
Omim http://omim.org/entry/176741
Immgen Expression
MEDIAN(HIGH IN B.GC.SP, PROB.FRBC.FL, PREB.FRD.FL, DC8+.TH, TGD.VG5+.ACT.IEL, NK.MCMV1.SP, T.8EFF.SP.OT1.D6.VSVOVA, TGD.TH, T.4SP24-.TH, T.8SP24-.TH, DC.LC.SK)
Gnf Expression
MEDIAN(HIGH IN TESTIS, FERTILIZEDEGG, OOCYTE, IMM.G1, IMM.G3, OSTEO GROUP, M1, EMBRYONIC.STEM TISSUES)
HIGH(HIGHER IN IMM.G1, IMM.G3, AND EMB GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000031004
Chromosome 7
Coordinate 135,698,957     (Assembly: GRCm38)    
Ref Base T
Codon Change atA/atG
Var Base C
Zygosity Heterozygous
Read Depth 246
Allele Frequency
T:R0.49
C:V0.51
Amino Acid Position 1449
Amino Acid Change I->M (Isoleucine -> Methionine)
Sample ID IGL01860
Median Base Quality 38
Backgrounds Balb/c:C57BL/6
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 49 Other Mutations

 Predictions 
Polyphen Score 0.35
Polyphen Prediction Benign
Sift Score 0
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved