Man2b2 - SNV Details



 Gene Information 
Gene Name Man2b2
Gene Description mannosidase 2, alpha B2 [Source:MGI Symbol;Acc:MGI:1195262]
Uniprot Name
CCDS Name
Gene GO
alpha-mannosidase activity; catalytic activity; mannose metabolic process; zinc ion binding; lysosome; carbohydrate metabolic process; mannosidase activity; carbohydrate binding; extracellular region; hydrolase activity
hydrolyzing O-glycosyl compounds
Homolog in other species MAN2B2
Immgen Expression
MEDIAN(HIGH IN DC.PDC.8-.SP, DC.PDC.8+.SP)
Gnf Expression
MEDIAN(HIGHER IN TESTIS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000029119
Chromosome 5
Coordinate 36,814,516     (Assembly: GRCm38)    
Ref Base T
Codon Change Agc/Ggc
Var Base C
Zygosity Heterozygous
Read Depth 16
Allele Frequency
T:R0.31
C:V0.69
Amino Acid Position 199
Amino Acid Change S->G (Serine -> Glycine)
Sample ID IGL01809
Median Base Quality 36
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 36 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.1
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved