Fam108c - SNV Details



 Gene Information 
Gene Name Fam108c
Gene Description family with sequence similarity 108, member C [Source:MGI Symbol;Acc:MGI:1917428]
Uniprot Name
CCDS Name
Gene GO
serine-type peptidase activity; hydrolase activity; cellular_component; proteolysis; biological_process
Homolog in other species FAM108C1
Immgen Expression
MEDIAN(HIGHER IN PROB.FRBC.FL, PREB.FRD.FL, T.DPSM.TH, TGD.TH)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000038459
Chromosome 7
Coordinate 84,151,289     (Assembly: GRCm38)    
Ref Base G
Codon Change Cgc/Tgc
Var Base A
Zygosity Heterozygous
Read Depth 25
Allele Frequency
G:R0.44
A:V0.56
Amino Acid Position 186
Amino Acid Change R->C (Arginine -> Cysteine)
Sample ID IGL01824
Median Base Quality 32
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 25 Other Mutations

 Predictions 
Polyphen Score 0.49
Polyphen Prediction Possibly damaging
Sift Score 0.06
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000112988:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Peptidase S9, prolyl oligopeptidase, catalytic domain Peptidase_S9 IPR001375 ENSMUSP00000112988 Pfam 172
296 Description available Search pathways
Dienelactone hydrolase Dienelactn_hydro IPR002925 ENSMUSP00000112988 Pfam 169
296 Description available Search pathways

 Availability Details 
Availability Cryopreserved