Rnf182 - SNV Details



 Gene Information 
Gene Name Rnf182
Old Gene Names for Rnf182 C630023l15rik
Gene Description ring finger protein 182 [Source:MGI Symbol;Acc:MGI:3045355]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; cytoplasm; zinc ion binding; ubiquitin-protein ligase activity; intracellular membrane-bounded organelle; protein binding; protein ubiquitination
Homolog in other species RNF182
Immgen Expression
MEDIAN(HIGHER IN NK GROUP, T.8MEM.LN, TGD.SPT.4NVE.PP, T.4FP3+25+.SP)
Gnf Expression
MEDIAN(HIGH IN CEREBELLUM)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000044164
Chromosome 13
Coordinate 43,668,032     (Assembly: GRCm38)    
Ref Base T
Codon Change Tgt/Cgt
Var Base C
Zygosity Heterozygous
Read Depth 18
Allele Frequency
T:R0.50
C:V0.50
Amino Acid Position 20
Amino Acid Change C->R (Cysteine -> Arginine)
Sample ID IGL01822
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 24 Other Mutations

 Predictions 
Polyphen Score 0.98
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Protein domains 
ENSMUSP00000062005:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Zinc finger, C3HC4 RING-type Znf_C3HC4_RING-type IPR018957 ENSMUSP00000062005 Pfam 20
67 Description available Search pathways
Zinc finger, RING-type Znf_RING IPR001841 ENSMUSP00000062005 Prosite_profiles 20
68 Description available Search pathways
Zinc finger, RING-type Znf_RING IPR001841 ENSMUSP00000062005 Smart 20
67 Description available Search pathways

 Availability Details 
Availability Cryopreserved