Polr3g - SNV Details



 Gene Information 
Gene Name Polr3g
Old Gene Names for Polr3g 2310047g20rik , Av275904
Gene Description polymerase (RNA) III (DNA directed) polypeptide G [Source:MGI Symbol;Acc:MGI:1914736]
Uniprot Name
CCDS Name
Gene GO
transcription
DNA-dependent; nucleus; positive regulation of interferon-beta production; innate immune response; defense response to virus; positive regulation of innate immune response
Homolog in other species POLR3G
Immgen Expression
MEDIAN(LOW IN GN.BM, HIGH IN B.GC.SP, PROB.FRBC.FL)
Gnf Expression
LOW/MEDIAN(HIGH IN RETINA, UMBLICALCORD, DIGIS, EPIDERMIS TISSUES,TRACHEA)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000035834
Chromosome 13
Coordinate 81,682,119     (Assembly: GRCm38)    
Ref Base G
Codon Change aCg/aTg
Var Base A
Zygosity Heterozygous
Read Depth 51
Allele Frequency
G:R0.49
A:V0.51
Amino Acid Position 145
Amino Acid Change T->M (Threonine -> Methionine)
Sample ID IGL01764
Median Base Quality 40
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 32 Other Mutations

 Predictions 
Polyphen Score 0.82
Polyphen Prediction Possibly damaging
Sift Score 0.01
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved