Rasal2 - SNV Details



 Gene Information 
Gene Name Rasal2
Old Gene Names for Rasal2 A330066m24rik
Gene Description RAS protein activator like 2 [Source:MGI Symbol;Acc:MGI:2443881]
Uniprot Name
CCDS Name
Gene GO
intrinsic to internal side of plasma membrane; regulation of small GTPase mediated signal transduction; cytoplasm; signal transduction; intracellular; protein binding; Ras GTPase activator activity; GTPase activator activity; positive regulation of Ras GTPase activity; phospholipid binding; negative regulation of Ras protein signal transduction
Homolog in other species RASAL2
Omim http://omim.org/entry/606136
Immgen Expression
MEDIAN(HIGH IN DC GROUP, MYELOID GROUP, BCELL GROUP)
Gnf Expression
MEDIAN
HIGH
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000070565
Chromosome 1
Coordinate 157,175,932     (Assembly: GRCm38)    
Ref Base C
Codon Change Gtg/Ttg
Var Base A
Zygosity Heterozygous
Read Depth 23
Allele Frequency
C:R0.43
A:V0.56
Amino Acid Position 404
Amino Acid Change V->L (Valine -> Leucine)
Sample ID IGL01759
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 63 Other Mutations

 Predictions 
Polyphen Score 0.42
Polyphen Prediction Benign
Sift Score 0.22
Sift Prediction tolerated

 Availability Details 
Availability Cryopreserved