Myo1f - SNV Details



 Gene Information 
Gene Name Myo1f
Old Gene Names for Myo1f C330006b10rik
Gene Description myosin IF [Source:MGI Symbol;Acc:MGI:107711]
MGI phenotype Mice homozygous for a knock-out allele exhibit impaired neutrophil migration and adhesion.
Uniprot Name
CCDS Name
Gene GO
motor activity; myosin complex; filamentous actin; positive regulation of cell migration; regulation of innate immune response; protein binding; regulation of actin cytoskeleton organization; cortical actin cytoskeleton; negative regulation of cell adhesion; neutrophil mediated immunity; ATP binding; defense response to Gram-positive bacterium; neutrophil degranulation; molecular_function
Homolog in other species MYO1F
Omim http://omim.org/entry/601480
Immgen Expression
MEDIAN(HIGH IN TGD GROUP, NK GROUP, T.8EFF.SP.OT1.D6.VSVOVA, T.4MEM.SP)
Gnf Expression
LOW/MEDIAN(HIGH IN IMM GROUP, OSTEO GROUP)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000024300
Chromosome 17
Coordinate 33,583,680     (Assembly: GRCm38)    
Ref Base C
Var Base A
Zygosity Heterozygous
Read Depth 79
Allele Frequency
C:R0.56
A:V0.44
Amino Acid Change Disrupted splicing
Splice Position 5
Sample ID IGL01744
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 34 Other Mutations

 Predictions 

 Availability Details 
Availability Cryopreserved