Parp14 - SNV Details



 Gene Information 
Gene Name Parp14
Old Gene Names for Parp14 1600029o10rik , Bc021340
Gene Description poly (ADP-ribose) polymerase family, member 14 [Source:MGI Symbol;Acc:MGI:1919489]
Uniprot Name
CCDS Name
Gene GO
transcription
DNA-dependent; cytoplasm; protein binding; nucleus; regulation of transcription
DNA-dependent; nucleotide binding; nucleic acid binding; plasma membrane; NAD+ ADP-ribosyltransferase activity
Homolog in other species PARP14
Omim http://omim.org/entry/610028
Immgen Expression
MEDIAN(HIGH IN GN.BM, B.FO.SP, B.MZ.SP, B1A.PC, NK GROUP, ABT GROUP, TACTIVATION GROUP)
Gnf Expression
MEDIAN(HIGH IN MACROPHAGES, OSTEOCLASTS)
LOW/MEDIAN(HIGH IN IMM GROUP, OSTEO GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000034422
Chromosome 16
Coordinate 35,858,600     (Assembly: GRCm38)    
Ref Base A
Codon Change Ttt/Ctt
Var Base G
Zygosity Heterozygous
Read Depth 26
Allele Frequency
A:R0.31
G:V0.69
Amino Acid Position 333
Amino Acid Change F->L (Phenylalanine -> Leucine)
Sample ID IGL01734
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 53 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 1
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved