Mki67 - SNV Details



 Gene Information 
Gene Name Mki67
Old Gene Names for Mki67 D630048a14rik
Gene Description antigen identified by monoclonal antibody Ki 67 [Source:MGI Symbol;Acc:MGI:106035]
Uniprot Name
CCDS Name
Gene GO
DNA metabolic process; chromosome
centromeric region; nuclear part; cytoplasm; cell proliferation; meiosis; condensed chromosome; protein C-terminus binding; intracellular; cellular response to heat; protein binding; nucleus; nucleolus; organ regeneration
Homolog in other species MKI67
Omim http://omim.org/entry/176741
Immgen Expression
MEDIAN(HIGH IN B.GC.SP, PROB.FRBC.FL, PREB.FRD.FL, DC8+.TH, TGD.VG5+.ACT.IEL, NK.MCMV1.SP, T.8EFF.SP.OT1.D6.VSVOVA, TGD.TH, T.4SP24-.TH, T.8SP24-.TH, DC.LC.SK)
Gnf Expression
MEDIAN(HIGH IN TESTIS, FERTILIZEDEGG, OOCYTE, IMM.G1, IMM.G3, OSTEO GROUP, M1, EMBRYONIC.STEM TISSUES)
HIGH(HIGHER IN IMM.G1, IMM.G3, AND EMB GROUP)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000031004
Chromosome 7
Coordinate 135,696,549     (Assembly: GRCm38)    
Ref Base T
Codon Change gAg/gGg
Var Base C
Zygosity Heterozygous
Read Depth 195
Allele Frequency
T:R0.53
C:V0.47
Amino Acid Position 2252
Amino Acid Change E->G (Glutamic acid -> Glycine)
Sample ID IGL01731
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 49 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.24
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000033310:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
K167R K167R IPR012568 ENSMUSP00000033310 Pfam 2176
2285 Description available Search pathways

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved