Slc22a16 - SNV Details



 Gene Information 
Gene Name Slc22a16
Old Gene Names for Slc22a16 4921504e14rik , 4921504e14rik
Gene Description solute carrier family 22 (organic cation transporter), member 16 [Source:MGI Symbol;Acc:MGI:1918090]
Uniprot Name
CCDS Name
Gene GO
cell differentiation; spermatogenesis; integral to membrane; amine transport; organic cation transmembrane transporter activity; acid secretion; organic cation transport; carnitine transport; transmembrane transporter activity; single fertilization; transmembrane transport; plasma membrane; sperm motility; carnitine transmembrane transporter activity; amine transmembrane transporter activity; multicellular organismal development
Homolog in other species SLC22A16
Omim http://omim.org/entry/608276
Immgen Expression
MEDIAN(LOWER IN DC8+.TH, TGD.VG5+.ACT.IEL)
Gnf Expression
HIGH
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000019834
Chromosome 10
Coordinate 40,585,018     (Assembly: GRCm38)    
Ref Base T
Codon Change aTc/aCc
Var Base C
Zygosity Heterozygous
Read Depth 101
Allele Frequency
T:R0.59
C:V0.41
Amino Acid Position 272
Amino Acid Change I->T (Isoleucine -> Threonine)
Sample ID IGL01667
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 35 Other Mutations

 Predictions 
Polyphen Score 0.96
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Protein domains 
ENSMUSP00000077428:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Major facilitator superfamily MFS IPR011701 ENSMUSP00000077428 Pfam 163
493 Description available Search pathways
General substrate transporter Sub_transporter IPR005828 ENSMUSP00000077428 Pfam 151
527 Description available Search pathways
Major facilitator superfamily domain, general substrate transporter MFS_dom_general_subst_transpt IPR016196 ENSMUSP00000077428 Superfamily 160
533 Description available Search pathways

 Availability Details 
Availability Progeny Cryopreserved