Aifm3 - SNV Details



 Gene Information 
Gene Name Aifm3
Old Gene Names for Aifm3 2810401c16rik , Ai840249
Gene Description apoptosis-inducing factor, mitochondrion-associated 3 [Source:MGI Symbol;Acc:MGI:1919418]
Uniprot Name
CCDS Name
Gene GO
oxidation-reduction process; mitochondrion; oxidoreductase activity; cytoplasm; metal ion binding; induction of apoptosis; activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; endoplasmic reticulum; cell redox homeostasis; flavin adenine dinucleotide binding; mitochondrial inner membrane; mitochondrial depolarization; electron transport chain; 2 iron
2 sulfur cluster binding; cysteine-type endopeptidase activator activity involved in apoptotic process
Homolog in other species AIFM3
Immgen Expression
MEDIAN(LOWER IN TGD.VG5+.ACT.IEL)
Novel Yes

 Mutation Information 
Mutation Type Splice
Ensembl ID ENSMUSG00000022763
Chromosome 16
Coordinate 17,502,786     (Assembly: GRCm38)    
Ref Base T
Var Base A
Zygosity Heterozygous
Read Depth 113
Allele Frequency
T:R0.45
A:V0.55
Amino Acid Change Disrupted splicing
Splice Position 2
Sample ID IGL01663
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 34 Other Mutations

 Predictions 
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved