Mrgprb5 - SNV Details



 Gene Information 
Gene Name Mrgprb5
Gene Description MAS-related GPR, member B5 [Source:MGI Symbol;Acc:MGI:3033121]
Uniprot Name
CCDS Name
Gene GO
integral to membrane; cellular_component; G-protein coupled receptor activity; G-protein coupled receptor signaling pathway; biological_process; molecular_function
Immgen Expression
MEDIAN(LOWER IN TGD.VG5+.ACT.IEL)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000070551
Chromosome 7
Coordinate 48,168,424     (Assembly: GRCm38)    
Ref Base T
Codon Change Ata/Cta
Var Base G
Zygosity Heterozygous
Read Depth 27
Allele Frequency
T:R0.52
G:V0.48
Amino Acid Position 188
Amino Acid Change I->L (Isoleucine -> Leucine)
Sample ID IGL01662
Median Base Quality 39
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 39 Other Mutations

 Predictions 
Polyphen Score 0.02
Polyphen Prediction Benign
Sift Score 0.06
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000091953:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
7TM GPCR, serpentine receptor class x (Srx) 7TM_GPCR_serpentine_rcpt_Srx IPR019430 ENSMUSP00000091953 Pfam 39
209 Description available Search pathways
GPCR, rhodopsin-like, 7TM GPCR_Rhodpsn_7TM IPR017452 ENSMUSP00000091953 Prosite_profiles 47
275 Description available Search pathways
G protein-coupled receptor, rhodopsin-like GPCR_Rhodpsn IPR000276 ENSMUSP00000091953 Pfam 47
275 Description available Search pathways

 Availability Details 
Availability Cryopreserved