Cd97 - SNV Details



 Gene Information 
Gene Name Cd97
Old Gene Names for Cd97 Aa409984
Gene Description CD97 antigen [Source:MGI Symbol;Acc:MGI:1347095]
MGI phenotype Mice homozygous for disruptions in this gene display a normal phenotype apart from mild granulocytosis.
Uniprot Name
CCDS Name
Gene GO
membrane; integral to membrane; cell adhesion; transmembrane signaling receptor activity; neuropeptide signaling pathway; protein binding; G-protein coupled receptor activity; cell surface receptor signaling pathway; G-protein coupled receptor signaling pathway; plasma membrane; calcium ion binding
Homolog in other species CD97
Omim http://omim.org/entry/601211
Immgen Expression
MEDIAN(HIGH IN GN.BM, B.FO.SP, B.MZ.SP, B1A.PC, NK GROUP, ABT GROUP, TACTIVATION GROUP)
Gnf Expression
HIGH(HIGHER IN IMM GROUPS, OESTEO GROUP, EPITH GROUP, BLADDER, UTERUS, OVARY, LUNG, TRACHEA AND ADIPOSETISSUE, PROSTATE, UMBLICALCORD)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000002885
Chromosome 8
Coordinate 83,727,935     (Assembly: GRCm38)    
Ref Base T
Codon Change aAc/aTc
Var Base A
Zygosity Heterozygous
Read Depth 19
Allele Frequency
T:R0.53
A:V0.47
Amino Acid Position 313
Amino Acid Change N->I (Asparagine -> Isoleucine)
Sample ID IGL01661
Median Base Quality 36
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 22 Other Mutations

 Predictions 
Polyphen Score 0.99
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved , Progeny Cryopreserved