Gga2 - SNV Details



 Gene Information 
Gene Name Gga2
Old Gene Names for Gga2 1200007e24rik
Gene Description golgi associated, gamma adaptin ear containing, ARF binding protein 2 [Source:MGI Symbol;Acc:MGI:1921355]
Uniprot Name
CCDS Name
Gene GO
trans-Golgi network; endosome membrane; ADP-ribosylation factor binding; intracellular; clathrin adaptor complex; protein binding; Golgi apparatus part; intracellular protein transport; vesicle-mediated transport; clathrin-coated vesicle
Homolog in other species GGA2
Immgen Expression
MEDIAN(HIGHER IN BCELL GROUP)
Gnf Expression
MEDIAN(HIGH IN EMB GROUP, PLACENTA)
MEDIAN(HIGH IN EMB GROUP, PLACENTA)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000030872
Chromosome 7
Coordinate 121,991,538     (Assembly: GRCm38)    
Ref Base T
Codon Change Acc/Gcc
Var Base C
Zygosity Heterozygous
Read Depth 34
Allele Frequency
T:R0.62
C:V0.38
Amino Acid Position 516
Amino Acid Change T->A (Threonine -> Alanine)
Sample ID IGL01584
Median Base Quality 35.5
Backgrounds Balb/c:C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 38 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.24
Sift Prediction tolerated

 Protein domains 
ENSMUSP00000033160:
Image provided by Ensembl

Full name Short name Interpro SeqRegionName Type Start End Description Search pathways
Coatomer/clathrin adaptor appendage, Ig-like subdomain Coatomer/clathrin_app_Ig-like IPR013041 ENSMUSP00000033160 Superfamily 459
603 Description available Search pathways
Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain Clathrin_a/b/g-adaptin_app_Ig IPR008152 ENSMUSP00000033160 Pfam 472
595 Description available Search pathways
Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain Clathrin_a/b/g-adaptin_app_Ig IPR008152 ENSMUSP00000033160 Smart 471
595 Description available Search pathways
Clathrin adaptor, gamma-adaptin, appendage Clathrin_g-adaptin_app IPR008153 ENSMUSP00000033160 Prosite_profiles 474
595 Description available Search pathways

 Availability Details 
Availability Cryopreserved