Pkn2 - SNV Details

 Gene Information 
Gene Name Pkn2
Old Gene Names for Pkn2 6030436c20rik , Ai507382 , Prkcl2 , Stk7
Gene Description protein kinase N2 [Source:MGI Symbol;Acc:MGI:109211]
Uniprot Name
Gene GO
cleavage furrow; apical junction complex; apical junction assembly; cell division; protein kinase activity; transcription
DNA-dependent; membrane; protein kinase C activity; apoptotic process; cytoplasm; signal transduction; cell adhesion; epithelial cell migration; midbody; intracellular; cell cycle; transferase activity
transferring phosphorus-containing groups; protein binding; nucleus; cytoskeleton; lamellipodium; histone deacetylase binding; regulation of cell motility; protein phosphorylation; regulation of transcription
DNA-dependent; protein tyrosine kinase activity; ATP binding; positive regulation of mitotic cell cycle; positive regulation of cell cycle cytokinesis; protein serine/threonine kinase activity
Homolog in other species PKN2
Immgen Expression
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000004591
Chromosome 3
Coordinate 142,839,231     (Assembly: GRCm38)    
Ref Base T
Codon Change Atg/Gtg
Var Base C
Zygosity Heterozygous
Read Depth 35
Allele Frequency
Amino Acid Position 161
Amino Acid Change M->V (Methionine -> Valine)
Sample ID IGL01574
Median Base Quality 39
Backgrounds Balb/c:C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 30 Other Mutations

Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.54
Sift Prediction tolerated
Druggable Yes, View known drug interactions

 Availability Details 
Availability Cryopreserved