Dock9 - SNV Details



 Gene Information 
Gene Name Dock9
Old Gene Names for Dock9 B230309h04rik , D14wsu89e , Aa959601 , Aw538057
Gene Description dedicator of cytokinesis 9 [Source:MGI Symbol;Acc:MGI:106321]
Uniprot Name
CCDS Name
Gene GO
Rho guanyl-nucleotide exchange factor activity; protein binding; binding; cellular_component; GTP binding; Rho GTPase binding; phospholipid binding
Homolog in other species DOCK9
Immgen Expression
MEDIAN/HIGH(LOW IN MYELOID GROUP, HIGH IN BCELL GROUP, ABT GROUP)
Gnf Expression
MEDIAN
HIGH(HIGHER IN IMM GROUP, NS GROUPS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000025558
Chromosome 14
Coordinate 121,653,084     (Assembly: GRCm38)    
Ref Base A
Codon Change cTg/cAg
Var Base T
Zygosity Heterozygous
Read Depth 23
Allele Frequency
A:R0.48
T:V0.52
Amino Acid Position 260
Amino Acid Change L->Q (Leucine -> Glutamine)
Sample ID IGL01567
Median Base Quality 35
Backgrounds Balb/c:C57BL/6
Source Walter and Eliza Hall Institute (WEHI-G1)
Other variants in this mouse 31 Other Mutations

 Predictions 
Sift Score 0
Sift Prediction deleterious

 Availability Details 
Availability Cryopreserved