Map2 - SNV Details



 Gene Information 
Gene Name Map2
Old Gene Names for Map2 Mtap2 , Mtap-2
Gene Description microtubule-associated protein 2 [Source:MGI Symbol;Acc:MGI:97175]
Uniprot Name
CCDS Name
Gene GO
dendrite morphogenesis; dendritic shaft; nuclear periphery; microtubule bundle formation; cytoskeletal regulatory protein binding; cellular response to organic substance; cytoplasm; central nervous system neuron development; cell body; axonogenesis; intracellular; dendrite development; microtubule; tubulin binding; dystroglycan binding; protein binding; peptidyl-threonine phosphorylation; neuronal cell body; neuron projection development; calmodulin binding; microtubule associated complex; dendrite
Homolog in other species MAP2
Immgen Expression
LOW(HIGH IN DC.LC.SK)
Gnf Expression
MEDIAN(HIGH IN NS GROUP)
MEDIAN(HIGH IN CEREBELLUM, OLFACTORYBULB, DORSALROOTGANGLION, HIPPOCAMPUS, AMYGDALA, FRONTALCORTEX, CEREBRALCORTEX, CORTEX, PREOPTIC, SUBSTANTIANIGRA, HYPOTHALAMUS)
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000015222
Chromosome 1
Coordinate 66,425,331     (Assembly: GRCm38)    
Ref Base C
Codon Change Ccc/Tcc
Var Base T
Zygosity Heterozygous
Read Depth 81
Allele Frequency
C:R0.60
T:V0.40
Amino Acid Position 266
Amino Acid Change P->S (Proline -> Serine)
Sample ID IGL01518
Median Base Quality 37
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 28 Other Mutations

 Predictions 
Polyphen Score 0
Polyphen Prediction Benign
Sift Score 0.62
Sift Prediction tolerated

 Availability Details 
Availability Progeny Cryopreserved