Lrig3 - SNV Details



 Gene Information 
Gene Name Lrig3
Old Gene Names for Lrig3 9030421l11rik , 9130004i02rik , 9430095k15rik
Gene Description leucine-rich repeats and immunoglobulin-like domains 3 [Source:MGI Symbol;Acc:MGI:2443955]
MGI phenotype Mice homozygous for a null allele or severely hypomorphic gene trap allele exhibit fusion of the lateral semicircular canal and circling behavior.
Uniprot Name
CCDS Name
Gene GO
integral to membrane; protein binding
Homolog in other species LRIG3
Immgen Expression
MEDIAN(HIGHER IN DC.LC.SK)
Gnf Expression
MEDIAN(HIGH IN RETINA, PITUITARY, DORSALROOTGANGLION, TRIGEMINAL, KIDNEY, LIVER, C2C12, UMBLICALCORD, NIH.3T3, OSTEOBLASTS, EPITH GROUP, IMM.G2, TRACHEA, PROSTATE, LUNG, BLADDER, UTERUS, OVARY, ADIPOSETISSUE, ADRENALGLAND)
LOW/MEDIAN
Novel Yes

 Mutation Information 
Mutation Type Non-synonymous
Ensembl ID ENSMUSG00000020105
Chromosome 10
Coordinate 126,008,698     (Assembly: GRCm38)    
Ref Base C
Codon Change aCa/aAa
Var Base A
Zygosity Heterozygous
Read Depth 48
Allele Frequency
C:R0.50
A:V0.50
Amino Acid Position 677
Amino Acid Change T->K (Threonine -> Lysine)
Sample ID IGL01510
Median Base Quality 38
Backgrounds C57BL/6NCrl
Source Australian Phenomics Facility (APF-G1)
Other variants in this mouse 45 Other Mutations

 Predictions 
Polyphen Score 1
Polyphen Prediction Probably damaging
Sift Score 0
Sift Prediction deleterious

 Availability Details 
Availability Progeny Cryopreserved